I've used Pihole for years as well as uBlock origin. When I don't have them it's painful. There are no solutions, only tradeoffs. Sometimes I need to disable uBlock. That's easy. Sometimes someone in the house needs to disable pihole. They can switch their DNS on I can temporarily (automatic toggle) Pihole.

I seriously do not know how people use the Internet without DNS filtering and script blocking. The Internet is a cespool of ads and trash. The tradeoff on these tools are worth it to me.