You kind of have the same set of hurdles as early Linux Desktop, as in fewer programs have been ported.
Instead of using wine to run windows apps you have waydroid that spins an android userspace inside a linux container, which has better compatibility since it’s not translating stuff like wine.

Privacy hardening is similar to desktop Linux, as in multiple solutions, everyone disagrees with everyone.

While Graphene currently has some upper hand on the privacy side (among other things, by being plug n play), it’s still a sand castle built on Google’s beach, fact of the matter is they don’t control the platform, so they have to walk on eggs undoing every fuckery Google introduces with every Android version.

At some point you have to question whether the time and effort doing mental gymnastics, chasing a moving target, unfucking android and reverse engineering play services is still worth it. I would say it never was, it actually strengthened the enemy by making android look like an open platform when in reality it is “iOS, but worse”.

So yeah, there’s work to be done on mobile Linux, but there’s no future in Android (forks).