I've never tried LSD, but from what I've read, psilocybin and LSD are pretty similar in their effect. I've been doing microdosing of psilocybin mushrooms for some time, but I can't say I've had any therapeutic improvements to talk about. Obiously, it greatly depends on the initial state of the person, so I could see this therapy helping in overcoming depression or addictions, but I personally prefer a full-blown trip once-twice a year to take a break from my daily routine and evaluate my position in life

Did weekly microdosing back in the day when I was still an office employee :) It took few trials before I found correct dose. You cant overdo it, becaue your focus will fly away. I meassured it in water and small shot glass. 100 mcgs in, 8 doses out. So around 13 mcg per microdose. Downside it you cannot macrodose at the same time, cos tolerance.
Use destiled water to avoid unwanted degradation. Keep in fridge.

In the past, I enjoyed mushroom microdoses. Helped my mood tremendously in a hard time period for me. I have never tried lsd micro doses. I prefer the less synthetic type tools.