Submit your computational protein designs. 1000 designs will be selected for experimental validation, 600 by the best ipSAE score, 200 selected by the community and 200 selected by a panel of experts.

Selected designs undergo experimental validation in the Adaptyv Lab. Proteins with the highest binding affinity against Nipah Virus Glyprotein G win the competition. There will be two rankings: De Novo and Lead Optimization.

Design

![Design a protein capable of neutralizing the Nipah virus, a pathogen with up to 75% mortality rate and high pandemic potential, currently lacking effective treatments.](https://m.stacker.news/113754)

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_Stage 1_
**Computational Design**
Submit your computational protein designs. 1000 designs will be selected for experimental validation, 600 by the best ipSAE score, 200 selected by the community and 200 selected by a panel of experts.

Submissions Open
Oct 27, 2025

Submissions Close
Nov 24, 2025

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_Stage 2_
**Experimental Validation**
Selected designs undergo experimental validation in the Adaptyv Lab. Proteins with the highest binding affinity against Nipah Virus Glyprotein G win the competition. There will be two rankings: De Novo and Lead Optimization.

Validation starts
Dec 1, 2025

Results released
Jan 6, 2026

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![](https://m.stacker.news/113755)