Stage 1 Computational Design Submit your computational protein designs. 1000 designs will be selected for experimental validation, 600 by the best ipSAE score, 200 selected by the community and 200 selected by a panel of experts.

Submissions Open Oct 27, 2025

Submissions Close Nov 24, 2025

Stage 2 Experimental Validation Selected designs undergo experimental validation in the Adaptyv Lab. Proteins with the highest binding affinity against Nipah Virus Glyprotein G win the competition. There will be two rankings: De Novo and Lead Optimization.

Validation starts Dec 1, 2025

Results released Jan 6, 2026