Bitcoin Safe had RPC connection to bitcoin core in the past (with the old BDK version). However the current BDK version doesnt have python bindings for the RPC client, and therefore Bitcoin Safe currently doesnt have RPC.
This would be a nice feature I'd like back too ;-)

You could ask nicely on https://github.com/bitcoindevkit/bdk-ffi to also create FFI-bindings for the RPC client. Maybe we get it :-)