New research is offering a fresh way to think about one of history’s most enduring enigmas: the Voynich Manuscript. Long described as the world’s most mysterious book, the early 15th-century manuscript is filled with an unknown script and strange illustrations of plants, astrological diagrams, castles, and human figures. Despite more than a century of analysis, no one has convincingly explained who wrote it, what it says, or even whether its text carries meaning at all.