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Yes. At least within the scope of the threshold. Active attackers will per their job description fuck you if you don't have cumulative controls.

For simplicity, pleb people amounts:

100k = 1
500k = 3
default = 6 

So 100k = 1 means 100k cumulative in the current block can go through, everything after that goes into tier 2, until 500k, requiring 3 confirmations, and everything after 500k in last(3) blocks goes into 6 confirmations. Could probably live with just the first and default tier at 3 though

This means that at current orphan rates I'd risk 100k per ~month.