The misaligned miner incentive problems are pretty big one IMO. 

TonyGiorgio

I can only speak for drive chains. The main arguments are:

https://fiatjaf.com/drivechain.html

what trade offs do you mean? I have looked briefly into drive chains during my research on prediction markets (Paul Sztorc did a lot of ground work for prediction markets on bitcoin using drive chains) and I have seen no real downside to them except that people are emotionally against the idea because it sounds like "shitcoins on bitcoin" (which is basically a feature not a bug lol)

bitcoin

Too Embarassed To Ask - Your Bitcoin & Lightning Questions Answered

I can only speak for drive chains. The main arguments are:

- It enables experimentation and new use cases for Bitcoin
- It solves conflicts and infighting
- It solves “scaling”
- It solves the blockchain security budget issue
- It keeps Bitcoin decentralized

source: https://fiatjaf.com/drivechain.html

what trade offs do you mean? I have looked briefly into drive chains during my research on prediction markets (Paul Sztorc did a lot of ground work for prediction markets on bitcoin using drive chains) and I have seen no real downside to them except that people are emotionally against the idea because it sounds like "shitcoins on bitcoin" (which is basically a feature not a bug lol)