Graphene is much more patched for security issues on Android than CalyxOS.
I'm not saying Calyx is worthless and it's probably a far better option than some random mainstream manufacturer roms in the privacy department. However, if the security of your phone is your top priority, Graphene is the best choice.
Where can I learn more about this?
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As already posted here:
Also on the Graphene website:
Here is a page that summarize what was recently patched and improved on both Graphene vs Calyx:
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