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In my city, and a number of others I've been to recently, there are giant permanent homeless encampments -- tent cities under bridges, on sidewalks, etc. People are milling around, blasted out of their minds on whatever drug. Some are probably pretty normal and relatively intact, but the ones who catch the eye are so far gone it breaks your heart.
Have no idea what can be done about this once it gets so far gone. It breaks your heart to see, I don't even care how or why they got there, it shows that society is not right if people are washing out of it in this way. The fact that there's record low unemployment, as remarked elsewhere, just makes it more poignant and baffling.