I usually don't respond at all. Particularly if it's just an acquaintance or a relative stranger. I don't have the time or energy to dig deeper and find out whether they're open-minded or not.

If it's someone like family or a close friend and their comment doesn't signal noticeable disdain or outright hostility to BTC, I'll take the time to gently ask what their preferred asset classes are and then point out why XYZ asset class has ABC problems and doesn't actually protect them from 123.

The goal there with people I know/I love is to be thought-provoking and hopefully get them to see BTC from a different angle.

Otherwise, I just keep quietly stacking and SWAN.