Whether or not the transactions eventually clear, they need to be consolidated be they become dust permanently. Those are two separate problems.

The mempool will relay CPFP transactions spending these right now. I would try to kill two birds with one stone and spend many of the small unconfirmed transactions while also boosting the effective feerate to at least 8 or 9 sats/vbyte. That's about the cheapest feerate I would feel comfortable with. Just do the math on the total vbytes of all transactions and make sure the child aggregation tx pays enough fee to effectively boost the total average feerate to your target.