I'm not going to ask if you're going to "take profits" because fiat isn't the measure of profits but bitcoin is. However, even with bitcoin you will eventually reach a point where the marginal utility of some goods and services will exceed the marginal utility of holding bitcoin even though it's going up in value.
So I'm asking: What good or service are you going to buy (other than daily necessities)? And at what price?
This is a question I've been reflecting, and I think now is a good time to figure out your values and form a plan and make your ideal life to come true when you are financially able to.
My own answer is that the first thing I'm going to buy is time. Time away from my part time fiat job, so that I can focus on my other projects fully and support myself without stress if/when those start generating income. I might quit my fiat job when my income is 5% of the size of my stack. I would reach that point at 200k/bitcoin. Eventually I would also buy some property to live in (with bitcoin-collateralized loan if I had the income), too, but from where and when, I don't know the details to.