Different for everyone, but a general rule would be when your Bitcoin stash is the majority of your total wealth.
If you fuck up, it's going to hurt.
Exactly, as bitcoin becomes a bigger part of your life the cost of a fuck up gets way more serious.
I often think about this while driving a car. The cost of a fuck up while driving can also be catastrophic. And you have to trust all the other maniacs out there not to fuck up. Yet, lots of people drive (and lots of people get fucked up because of driving).
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