Hey :)
The biggest issue facing Monero-enabled FediMints is the exchange rate differences, as the "MSP" (Monero Service Provider, in place of LSP) has to be willing to take on exchange rate differences between Bitcoin and Monero.
On the "Monero-only" side, thankfully we don't need any of the "easy Lightning" or "strong privacy" offered by FediMints natively, so I only really see Monero being applicable in the MSP sense for Bitcoin-based FediMints in the future.