I switched to knuckle pushups last month, because they're easier on my wrists. It was interesting how even that slight of a change had a noticeable impact on the difficulty of the workout.
I alternate. Sometimes I do them on my knuckles. Some times I do them declined. Gotta keep it fresh.
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I have been slightly varying my hand placement the whole time, so I didn't expect to notice anything from switching to knuckles.
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