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This is way out of my wheelhouse, but ... I am will be needing to look for a diagramming tool myself, and I refuse to use a proprietary Microsoft product, so I googled for: Visio alternative free and found:
and
Top 10 Microsoft Visio Alternatives And Competitors In 2022 https://www.softwaretestinghelp.com/visio-alternatives/
and
The ones that kept recurring among my search were: Microsoft Visio, and LucidCharts
Here's an article describing Layers with LucidCharts:
Interactive Diagrams: 3 Ways to Use Hotspots and Layers in Lucidchart https://www.lucidchart.com/blog/interactive-diagrams-3-ways-to-use-hotspots-and-layers
Also
Work with layers in diagrams.net https://www.diagrams.net/doc/layers
Miro looks nice, ... but does not have Layers.
I had used Dia some years ago. I liked Visio better. No idea if Dia has layers though I saw something called "Layer objects".
That was the extent of my research so no idea what others have support for layers.
Hope this helps.