Every day, he must organize his solitary existence in an abandoned city, emptied of its inhabitants by a strange epidemic. An incurable virus that forces humans to feed on blood and compels them to flee the sun's rays... Every night, vampires hunt him to the doors of his home, a fragile refuge against a horde with familiar faces of his former neighbors or his own wife. Every night is a nightmare for the last man, the ultimate survivor of a now legendary species.