I didn't write the first version of it. But I took over maintainership from jgarzik many years ago and got it into a more useful shape.
Afaik there are no guides for installing it yet and there are some quirks with up/downgrading some crypto dependencies in Ubuntu (apt), other Linux distros and MacOS (brew). Are you aware of that?
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I mean, installing python-bitcoinlib is just the usual pip3 install python-bitcoinlib
I recently made a new release that I think fixes the main crypto dependency issue with missing ripemd160 support.
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