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Holy moly. $400 Billion is spent on illegal drugs each year:
"With estimates of $100 billion to $110 billion for heroin, $110 billion to $130 billion for cocaine, $75 billion for cannabis and $60 billion for synthetic drugs, the probable global figure for the total illicit drug industry would be approximately $360 billion. Given the conservative bias in some of the estimates for individual substances, a turnover of around $400 billion per annum is considered realistic."
I wonder which has the highest profit margin. I'd bet synthetics.