What will it take to detect dark matter—the invisible, nigh-intangible substance that might make up five-sixths of all matter in the universe? Dark matter should be all around us, exerting tiny effects on normal matter, but searches have come up empty so far. But a new study suggests that a strategy employing machine learning could help quantum sensors finally hunt it down. Such hyper-sensitive sensors may also have other applications, such as GPS-free navigation, the detection of underground bunkers, and the discovery of gravitational ripples in space-time from the moments after the Big Bang.