The Energy Model of Insulin Resistance hypothesizes that RBD seed oil consumption can promote cellular oxidative stress, forcing cells to change their fueling strategy to reduce oxidative stress. This is accomplished by increasing aerobic glycolysis to minimize fat oxidation. Observed in both cancerous and insulin resistance cells, aerobic glycolysis is also known as the Warburg Effect. While beneficial to individual cells, at the whole-organism level, it disrupts intravascular glucose homeostasis, ultimately elevating insulin and counter-regulatory hormones (CRH) simultaneously.
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