Warren Buffett's Berkshire Hathaway has significantly outperformed the S&P 500 over the past several decades. Since 1965, Berkshire Hathaway's stock has returned 5,502,284%, compared to the S&P 500's total return of 39,054%, including dividends. This translates to a compounded annual gain of 19.9%, nearly double the S&P 500's 10.4% annual return