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I experienced an irregular heart rhythm while using kratom once so I stopped. I believe I read once that some people use kratom to help cut opiate addiction.
I think about this bizarre Jim Morrison 'interview' dubbed over by Rick Rubin where Morrison admits to being 'an alcoholic type person' and adds that the 'Irish are more the alcoholic type.' The interview is worth listening to in its entirety as I think it gave a window into the vulnerable, if not slightly misanthropic, poet-Morrison. It is beautiful, haunting and a bit tragic listening to his voice. Anyway it made me reflective on the cultural baggage that drinking has, wherein comes packaged the specters of both intergenerational traumas and festivities.