Of course it can, and sometimes it definitely does (that's a gut feeling induced by simple inference from standard behaviour on tech space).

However, VPNs are also used for work reasons, so I believe ISPs can not discriminate between the case of someone wanting to hide and someone who use VPNs for work, and thus don't pay much attention to whoever use it. Actually, I don't even know how the ISP can know you are using a VPN, so I realize I am writing almost meaningless words.