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Adults with chronic insomnia who used melatonin for a year or longer faced a 90 percent higher risk of developing heart failure within five years compared to non-users.
The preliminary analysis, presented Monday at the American Heart Association’s Scientific Sessions 2025, tracked more than 130,000 adults diagnosed with insomnia. Among those who took melatonin for more than a year, 4.6 percent developed heart failure, compared with 2.7 percent of nonusers.
91 sats \ 0 replies \ @Scoresby 14h
basically, there's no free lunch. You gotta be so careful when taking any quantity of refined substances.
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5 sats \ 0 replies \ @nichro 11h
For what it's worth, I think OTC dosage (1mg 3mg sometimes 5mg) is way too strong.
Break a tablet in half or quarter. 0.1mg to 0.5mg still works, often just as well as 1-3mg. Pretty sure there were studies to back this up.
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Co-relation does not equal causation. This is an observational study, it does not show that melatonin causes heart failure.
FTA:
“This doesn’t prove that melatonin directly causes heart failure,” said Nnadi, noting that the study was observational. People who take melatonin every night may simply have more severe insomnia, which itself could raise heart risks.
Note also that the melatonin users in the study were prescribed melatonin, which probably means it was a much higher dose than what over-the-counter users take, often 1-3mg. But those details weren't mentioned in this article.
And this:
The research could only track prescribed melatonin, since some over-the-counter use isn’t recorded in medical records. That means some people counted as “nonusers” may have taken melatonin without telling their doctors.
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0 sats \ 0 replies \ @j7hB75 12h
What about with kids?
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Wow glad I never went down this path of taking melatonin
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