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It sounds almost cliché, but the Westphalian nation-state model we've been under since 1648 is obsolete now. Networks of individuals themselves, regardless of their geographic location, can attain the sovereignty that heretofore has been limited to nation-states. Like tribes in cyberspace, where each individual person is a node in the network.
That doesn't mean political models like "The United States" or "France" will disappear. But I think we'll soon recognize the distinction between government and governance, between nation and nation-state, and so on.
It's rather difficult to predict the full ramifications of this, for the same reason someone in 1023 didn't yet realize what "The Middle Ages" would become.