I'm fully ok with saying "I don't know" as a scientist (I say that at least a few times a week to students and colleagues during discussions). Lots of things that were intangible have become tangible over time, so I believe there are even more such transitions to come in centuries ahead. I like to observe these intangibles, and ponder about them, but I specifically try to avoid making definite claims. I don't need a higher power (God, etc) to make sense of them, I just accept them as things we can't explain yet (or may never be able to explain). I'm happy with this worldview, it works for me. And it may not work for others.