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Yes, just keep it in mind, because is better to be well organized from the beginning. Is not really necessary to apply this only when you have a desktop public routing node... you can apply it also for private nodes like Zeus, Blixt , Breez, Electrum, Alby, LNbits, Bitkit etc.
Even if you use only custodial LN accounts for spending but keep the UTXO in your own self-custody wallets, when you move funds from/to your cold stash, you must do it wisely.