Combining your coinjoined outputs is slightly less private than spending them individually, but you generally shouldn't worry about this unless you are a huge whale. If there's still any doubt, you can remix an extra time before spending.

For the absolute maximum privacy, you can make small or medium sized payments directly inside a coinjoin. This feature is currently only available in Wasabi's RPC, the UX for the GUI is still being worked on. https://docs.wasabiwallet.io/using-wasabi/RPC.html#payincoinjoin