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From 2009 through 2024, a total of 889 patients underwent randomization to the exercise group (445 patients) or the health-education group (444 patients). At a median follow-up of 7.9 years, disease-free survival was significantly longer in the exercise group than in the health-education group (hazard ratio for disease recurrence, new primary cancer, or death, 0.72; 95% confidence interval [CI], 0.55 to 0.94; P=0.02). The 5-year disease-free survival was 80.3% in the exercise group and 73.9% in the health-education group (difference, 6.4 percentage points; 95% CI, 0.6 to 12.2). Results support longer overall survival in the exercise group than in the health-education group (hazard ratio for death, 0.63; 95% CI, 0.43 to 0.94). The 8-year overall survival was 90.3% in the exercise group and 83.2% in the health-education group (difference, 7.1 percentage points; 95% CI, 1.8 to 12.3). Musculoskeletal adverse events occurred more often in the exercise group than in the health-education group (in 18.5% vs. 11.5% of patients).
This was following both surgery and chemo.
20 sats \ 1 reply \ @grayruby 2 Jun
Interesting. Does it specify the type, frequency and intensity of the exercise?
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from here:
The exercise intervention met its goal of increasing moderate-to-vigorous physical activity from baseline by about 10 metabolic equivalent task-hours per week throughout the entire 3-year intervention. This increase is the equivalent of adding about 45-60 minutes of brisk walking three or four times per week or 25-30 minutes of jogging three or four times per week, said Booth and colleagues.
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10 sats \ 2 replies \ @398ja 3 Jun
This is because during physical exercise, your muscles consume the glucose that the cancer cells would otherwise need to grow, so I've heard...
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21 sats \ 1 reply \ @k00b OP 3 Jun
I’m not sure it’s that simple. Exercise has a lot of (positive) effects on the body. That’s a decent hypothesis though.
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You're right tu highlight the complexity of this issue.
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